3rd Biology for Physics Conference - BPC 2026, Barcelona (España). 06-10 septiembre 2026
Resumen:
We model T cell recognition as Bayesian inference using a universal, unifying framework for existing T-cell phenotypic mechanisms. Antigen discrimination peaks when stochastic encounter durations match internal receptor kinetics. Irreversible commitment steps act as informational filters, maximising mutual information and explaining how physical time constraints shape immune receptor architectures.
Fecha de publicación: 06-sep-2026
Cita:
M. Castro, "Information-Geometric Selection in T-Cell Receptor Cascades: How Noise Shapes Ligand Discrimination", presentado en 3rd Biology for Physics Conference - BPC 2026, Barcelona, España, 06-10 septiembre 2026
IIT-26-241C_abstract
